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Effective Raw Pharmaceutical Powder Bicalutamide Purity 99% for Anti-Prostate Cancer

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Effective Raw Pharmaceutical Powder Bicalutamide Purity 99% for Anti-Prostate Cancer

Large Image :  Effective Raw Pharmaceutical Powder Bicalutamide Purity 99% for Anti-Prostate Cancer

Product Details:

Place of Origin: CHINA
Brand Name: TJ
Certification: ISO
Model Number: 90357-06-5

Payment & Shipping Terms:

Minimum Order Quantity: 1g
Price: negotiable
Packaging Details: Discreetly packaging ensure 100% securityq
Delivery Time: 3-7 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: bulk stock
Detailed Product Description
Name: Bicalutamide Appearance: White Powder
Purity: 99%

Effective Raw Pharmaceutical Powder Bicalutamide Purity 99% For Anti-Prostate Cancer

Product name: Bicalutamide
Alias: Cosudex; BicalutaMide API; 25mg; Bicaiutamide; ODEX;
CAS Number: 90357-06-5
Molecular formula: C18H14F4N2O4S
Molecular weight: 430.37300
Appearance and properties: off-white crystalline solid
Density: 1.52 g/cm3
Melting point: 191-193°C
Boiling point: 650.3oC at 760 mmHg
Flash point: 347.1oC
Refractive index: 1.577
Storage conditions: Store in original container in a cool dark place.
 

Description:

Bicalutamide is a member of the nonsteroidal antiandrogen (NSAA) group of medications. It works by blocking the androgen receptor (AR), the biological target of the androgen sex hormones testosterone and dihydrotestosterone (DHT). It does not lower androgen levels.[6] The medication can have some estrogen-like effects in men.

Bicalutamide is well-absorbed, and its absorption is not affected by food. The terminal half-life of the medication is around one week. It is believed to cross the blood-brain barrier and affect both the body and brain.

 

Application:

Bicalutamid is used primarily in the treatment of early and advanced prostate cancer. It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone (GnRH) analogue or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), and as a monotherapy at a dosage of 150 mg/day for the treatment of stage C or D1 locally advanced prostate cancer (LAPC). Although effective in mPC and LAPC, bicalutamid is no longer indicated for the treatment of localized prostate cancer (LPC) due to negative findings in the Early Prostate Cancer (EPC) trial.

Uses:

Bicalutamid is used to treat prostate cancer that has spread to other areas of the body. It is used in combination with hormone treatment. This medication works by blocking the action of male hormones in the prostate, slowing growth of the tumors.

How to use bicalutamid?

Read the Patient Information Leaflet if available from your pharmacist before you start taking bicalutamid and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

COA:
 


Product name

Bicalutamide

CAS No.
90357-06-5
Outer Packing
1kg/ Foil bag

Production date
2016.06
Shelf life
2018.05

Standard adopted
USP 36

Items of analysis

Specification

Results

Appearance
White or off-white crystalline powder Conform

Identification
HPLC RT Conform
Solubility Freely soluble in tetrahydrofuran and in acetone, soluble in acetonitrile, sparingly soluble in methanol, slightly soluble in alcohol Conform

Water
≤0.2% 0.01%

Residue on ignition
≤0.1% 0.09%

Particle size
90%<10um, 50%<5um Conform

Heavy metals
≤10ppm Conform

Bicalutamide aminobenzonitrile
≤0.1% Not detected

Bicalutamide related compound A isomer
≤0.1% Not detected

Bicalutamide related compound A isomer
≤0.1% Not detected

Des-fluoro bicalutamide
≤0.2% Not detected

2-Fluoro Bicalutamide
≤0.2% <0.01%

Deoxybicalutamide
≤0.2% Not detected

Bicalutamide sulfide
≤0.1% Not detected

Individual unspecified impurity
≤0.1% 0.02%

Total impurities
≤0.5% 0.04%

Assay
98.0%~102.0%(on dried basis) 99.6%

Ethyl acetate
≤5000ppm 32ppm

Tetrahydrofuran
≤720ppm Not detected

Dichloromethane
≤600ppm Not detected

Toluene
≤890ppm Not detected

Methanol
≤3000ppm Not detected

Acetone
≤5000ppm 251ppm

Conclusion

Qualified


 

The quality control process:

1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.


2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.


3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.


4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.

 

Our Advantages:

1. Rich experience: Our company is a professional production leading factory in China in pharmaceutical area of many years.

2. Top quality: High quality guaranteed, once any problem is found, the package would be reshipped for you .

3. Security Shipping: Shipping by express (FedEx,UPS,DHL,EMS), by air. The most professional forwarder would be recommanded for you.

4. Fast delivery: We have stock, so we can delivery quickly once payment is received.

5. Quality service: We will give you warm after-sale service,if any question we will reply you within 24 hours.

6. Competitive prices: A discount would be given when you make a large order.

Contact Details
zhuhai TianJian Chemical Co.,Ltd.

Contact Person: Henry

Tel: +8617671438862

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