Product Details:
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Name: | Guaiacol | Appearance: | Colorless Liquid |
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Purity: | 99% | Color: | White Color |
High Light: | safety solvents,natural solvents |
99.8% Purity Pharmaceutical Raw Materials Guaiacol as Steroids Solvent
Description:
Guaiacol is a phenolic compound with a methoxy group and is the monomethyl ether of catechol. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes. It therefore serves as a reducing co-substrate for COX reactions. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. It is a yellowish aromatic oil that is now commonly derived from guaiacum or wood creosote. It is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a potent scavenger of reactive oxygen radicals and its radical scavenging activity may be associated with its effect on cell proliferation. Guaiacol is also used in the preparation of synthetic vanillin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.
Basic information:
Formal Name: 2-methoxy phenol
CAS Number: 90-05-1
Molecular Formula: C7H8O2
Formula Weight: 124.1
Purity: ≥98%
Formulation: A colorless liquid
λmax: 220, 277 nm
Storage: Room temperature
Shipping: Room temperature in continental US; may vary elsewhere
Stability: ≥ 1 year
Melting point: 26-29 °C(lit.)
Boiling point: 205 °C(lit.)
Density: 1.129 g/mL at 25 °C(lit.)
vapor density: 4.27 (vs air)
vapor pressure: 0.11 mm Hg ( 25 °C)
refractive index: n20/D 1.543(lit.)
Flash point:180 °F
storage temp: Refrigerator
solubility: H2O: insoluble
form Liquid After Melting
pka9.98(at 25ºC)
color Clear colorless to light yellow
PH5.4 (10g/l, H2O, 20ºC)
Water Solubility 17 g/L (15 ºC)
FreezingPoint: 28ºC
COA:
Product name | Benzyl benzoate | ||
CAS No. | 120-51-4 | Outer Packing | 220KG |
Production date | 2016.10.10 | Shelf life | 2017.10.09 |
Items of analysis | Specification | Results | |
Appearance | Colorless or light yellow oil liquild | light yellow oil liquild | |
refractive index(20ºC) | 1.5680-1.5700 | 1.5700 | |
proportion(25/25ºC) | 1.118-1.122 | 1.119 | |
Assay | 99.0-100.5% | 99.9% | |
chroma,Hazen | 150-240 | 190 | |
residue | ≤0.1% | 0.02% | |
acidity | ≤0.2ml, 0.1mol/1NaOH/2g | 0.12 | |
Conclusion | Qualified |
Uses and chemical reactions:
Guaiacol is a precursor to various flavorants, such as eugenol and vanillin. An estimated 85% of the worlds supply of vanillin comes from guaiacol. The route entails condensation of glyoxylic acid with guaiacol to give mandelic acid, which is oxidized to produce a phenylglyoxylic acid. This acid undergoes a decarboxylation to afford vanillin.
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Safety:
Methoxyphenols are potential biomarkers of biomass smoke exposure; e.g., from inhalation of woodsmoke. Dietary sources of methoxyphenols overwhelm the contribution from inhalational exposures to woodsmoke.
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